Folate (Vitamin B9 / 5-MTHF) in Multivitamins
Folate is a B-vitamin essential for DNA synthesis, cell division, and neural tube development during pregnancy. The methylated form (5-MTHF) is the bioactive form that bypasses MTHFR gene variants.
Benefits
- ✓Prevents neural tube defects during early pregnancy
- ✓Essential for DNA synthesis and cell division
- ✓Reduces homocysteine levels (heart disease risk factor)
- ✓Supports red blood cell production
- ✓Critical for brain and spinal cord development in fetuses
Recommended Daily Value
400mcg DFE for adults; 600mcg DFE during pregnancy
Food Sources
- Leafy green vegetables
- Legumes
- Fortified grains
- Asparagus
- Avocado
Scientific Reference
Bailey LB et al. The New Recommended Dietary Allowances for Folate. J Nutr. 1998;128:1988S-1996S.
Multivitamins Containing Folate (Vitamin B9 / 5-MTHF)
The most evidence-based daily multivitamin on the market. Every one of its 26 ingredients is backed by human RCTs at the exact dose used in clinical trials — methylated B vitamins, glycinate-form minerals, 200mg hyaluronic acid for skin health, TMG for cognition and exercise, and microencapsulated carotenoids for eye protection. It deliberately excludes Vitamin A and E based on safety research, and consolidates 6–8 separate supplements into one formula.
Transparent, traceable ingredients in a minimalist formula designed specifically for women — excellent for those who value clean labels.
Best-in-class for bioavailability — Thorne uses superior active forms of every nutrient with no unnecessary additives.
Best organic prenatal vitamin — USDA Certified Organic with methylfolate and whole-food iron that's gentle on the stomach.
Best-tasting kids multivitamin with premium nutrients (methylcobalamin, omega-3 DHA) that most gummies skip.
Most affordable complete multivitamin for men over 50 — covers the basics with added lycopene and higher B12.
The most widely recommended pharmacy multivitamin for women over 50 — complete, affordable, and clinically studied.
Best budget multivitamin for women — USP Verified, affordable, and covers all the essentials including iron.