Vitamin B6 (Pyridoxine / P5P) in Multivitamins

Informational only: This page is not medical advice. Consult a healthcare provider before starting supplements.

Vitamin B6 (pyridoxine) is a water-soluble vitamin that serves as a coenzyme for over 100 enzyme reactions. Pyridoxal-5-Phosphate (P5P) is the active coenzyme form, superior to pyridoxine HCl as it requires no conversion.

Benefits

  • Coenzyme for amino acid and neurotransmitter metabolism
  • Supports production of serotonin, dopamine, and GABA
  • Reduces homocysteine levels (alongside B12 and folate)
  • Supports immune function and antibody production
  • P5P form is directly usable — no liver conversion needed

Recommended Daily Value

1.3–1.7mg for adults; upper limit 100mg/day

Food Sources

  • Beef liver
  • Tuna
  • Salmon
  • Chickpeas
  • Poultry

Scientific Reference

Stover PJ. Vitamin B6. In: Coates PM et al, eds. Encyclopedia of Dietary Supplements. 2010.

Multivitamins Containing Vitamin B6 (Pyridoxine / P5P)

1.28mg
$55
capsule

The most evidence-based daily multivitamin on the market. Every one of its 26 ingredients is backed by human RCTs at the exact dose used in clinical trials — methylated B vitamins, glycinate-form minerals, 200mg hyaluronic acid for skin health, TMG for cognition and exercise, and microencapsulated carotenoids for eye protection. It deliberately excludes Vitamin A and E based on safety research, and consolidates 6–8 separate supplements into one formula.